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In which racial background is systemic lupus erythematosus (SLE) least commonly found?

  1. African Americans

  2. Asians

  3. Hispanics

  4. Mediterraneans

The correct answer is: Mediterraneans

Systemic lupus erythematosus (SLE) is an autoimmune disease that exhibits variable prevalence among different racial and ethnic groups. Research consistently shows that SLE is most commonly diagnosed in African Americans, followed by Hispanic and Asian populations. However, Mediterranean populations generally show a lower prevalence of SLE compared to these other groups. The reason for the reduced incidence of SLE in Mediterranean individuals may be attributed to genetic, environmental, and lifestyle factors that influence the disease's pathogenesis and prevalence. Additionally, cultural differences in disease awareness and healthcare access could also play a role in the lower reported cases within Mediterranean populations. Understanding these epidemiological aspects highlights the importance of considering demographic influences on disease prevalence, which is essential for proper diagnosis and treatment in diverse populations.