Family Nurse Practitioner Exam

When dealing with a patient suspected of having a viral upper respiratory infection, which of the following treatments is least advisable?

1. Saline nasal spray

2. Pseudoephedrine

3. Ibuprofen

4. Oral prednisone

The correct answer is: Oral prednisone

When treating a patient suspected of having a viral upper respiratory infection, the recommendation to avoid oral prednisone stems from its potential suppressive effects on the immune system. Prednisone, a corticosteroid, can inhibit the body's natural inflammatory response, which plays a crucial role in fighting off viral infections. The goal in managing viral upper respiratory infections is often symptomatic relief while allowing the body's immune system to function effectively. In contrast, saline nasal spray is beneficial for moisturizing nasal passages and providing relief from nasal congestion without negative impacts on immune response. Pseudoephedrine is a decongestant that can effectively alleviate nasal congestion, making it a common choice for symptomatic treatment. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce fever and alleviate pain, contributing to overall comfort during the illness. Therefore, while other treatments can support the patient's symptoms effectively, oral prednisone is least advisable as it may hinder the immune response necessary for recovery from a viral infection.