Family Nurse Practitioner Exam

Which ADHD medication is classified as a norepinephrine reuptake inhibitor?

1. Dexmethylphenidate

2. Mixed salts of amphetamine

3. Methylphenidate

4. Atomoxetine

The correct answer is: Atomoxetine

Atomoxetine is classified as a norepinephrine reuptake inhibitor. Unlike stimulant medications commonly used to treat ADHD, such as methylphenidate and amphetamines, which primarily enhance the release of dopamine and norepinephrine, atomoxetine works by selectively inhibiting the reuptake of norepinephrine in the brain. This mechanism helps to increase the levels of norepinephrine available in the synaptic cleft, which can contribute to improved attention and focus in individuals with ADHD. Additionally, atomoxetine's non-stimulant nature makes it a suitable option for patients who may not respond well to stimulant medications or who have a history of substance abuse, as it carries a lower risk of addiction. Its unique pharmacological profile positions atomoxetine as a valuable alternative in ADHD management, particularly for those who require sustained treatment without the stimulant side effects.